Research & Development

No matter what phase you’re at in your product’s development cycle, we can help you. We’ll help you obtain the tools you need to develop your drug and nutraceutical therapies.

Our Process

With our cutting-edge laboratories, we are able to offer a complete suite of services at any stage of your developement process.

Transduction Pathways

Our laboratories offer a variety of assay platforms and instruments for cell-based assay services using western-blot, ELISAs approaches (electrochemiluminescence, chemiluminescence, fluorescence and colorimetry) and laser scanning confocal microscopy for the quantification of different cellular phosphorylated proteins (cellular kinase assays, etc..) and the identification of signaling pathways impacted by drugs for early drug discovery.

PK/PD and Bioavailability

As part of PK studies, we can determine the bioavailability (following oral, intraperitoneal, subcutaneous, topical/epicutaneous delivery) of small molecules as well as their tissue distribution using a deuterated standard and an LC-MS/MS approach and identify compounds with oral bioavailability and BBB penetration potential.


The most convenient route of drug administration is peroral and requires drug molecules to be absorbed from the gastroinstestinal track and enter the systemic circulation. As a precursor to in vivo PK studies, we offer several in vitro cellular models to predict gastrointestinal absorption and blood-brain barrier (BBB) penetrability for small molecules as well as assays to identify potential interactions with drug transporters.

Mechanism of Action

We offer a variety of cell free and cell-based assays to assess the mechanism of action of small molecules including:

  • Biolayer interferometry to measure biomolecular interactions between small molecules/proteins, peptides/proteins, protein/protein interactions for kinetic and binding affinity determination
  • Cell free enzymatic assays (kinases, proteases, etc…)
  • Overexpression and genetic suppression of the molecular target in cellular models for target validation and target engagement studies
  • Identification of the protein targets for drugs following click chemistry and a proteomic approach

Pathology (CNS)

We are equipped for processing pathological specimens and performing various histological stains and immunostaining and produce image analysis/quantification of various histological markers in pathological specimen following light, fluorescence and laser scanning confocal microscopy for colocalization studies. Example of studies include the detection and quantification of amyloid plaques, degenerating neurites, microgliosis/astrogliosis, tau hyperphosphorylation/oligomerization/aggregation in animal models of Alzheimer’s disease; analysis of demyelination/immune cell infiltration in the spinal cord of a mouse model of MS, etc.

Medicinal Chemistry / SAR

We can provide various services for early drug discovery projects including:

  • Click chemistry for target identification
  • Synthesis of API and analogs
  • Screening of compounds (focused library, diversity sets, etc…) using cell free and cell-based assays for the identification of hits/chemical scaffolds and the establishment of structure activity relationships (SAR) to orient the rational design of compounds with higher potency

In Vivo & In Vitro Assays

Utilize our collection of validated in-house models.

Alzheimer’s Disease

Gulf War Syndrome



Multiple Sclerosis

Traumatic Brain Injury

Talk to Our Experts

We can help every step of the way.

Frequently Asked Questions

Have a question that isn’t answered here?

Send us a message and we’d be happy to answer any and all questions you might have.

I’m not sure where to even start, can you help me?

Absolutely, we offer consultation services to develop a project plan that fits your needs and budget.

Can you help me compare my product delivery system to others in the marketplace?

Our in vitro assays offer a cost effective means to evaluate the effects of various delivery methods.

I am unsure of the integrity of my incoming ingredients, can you help?

We offer an Identity Testing service that utilizes Mass Spectrometry to verify the integrity of your products at a level that is generally much higher than the industry standards.

Do you offer in-house sample analysis?

Yes, we have many methods, including mass spectrometry, of generating sample data in our facility.

Do you have a physical lab in the United States?

Yes, we are located in beautiful, sunny Sarasota and we are always happy to schedule a tour of our facilities.

Are your services flexible? I’m uncertain about my timeline and budget, is this a problem?

This is not a problem, we strive to work with our clients to fit their needs, whether that is timeline, budget, or data needs.